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---------------------------------------------------------------- FOR IMMEDIATE RELEASE

CONTACTS: César García,
President and Chief Executive Officer
818-709-1244 Ext. 123 or
Ron Stabiner, The Wall Street Group, Inc.
212-888-4848

IRIS INTERNATIONAL TO RELEASE FIRST QUARTER 2006 FINANCIAL RESULTS AND HOST CONFERENCE CALL ON TUESDAY, MAY 9

CHATSWORTH, Calif., April 20, 2006 — IRIS International, Inc. (NASDAQ: IRIS) today announced that it will release financial results for the first quarter ended March 31, 2006 at the close of market on Tuesday, May 9, 2006. The Company will also hold a conference call to review the results at 4:30 p.m. Eastern time that afternoon.

To participate, dial 1-800-289-0528 approximately 10 minutes before the conference call is scheduled to begin. Hold for the operator and reference the IRIS International conference call. International callers should dial 913-981-5522.

The conference call may also be accessed by means of a live audio Web cast on the Company's Web site at www.proiris.com, or at www.vcall.com, the Web cast service provider. The conference audio cast will also be available for replay on both Web sites for 30 days from the date of the broadcast.

The Company

IRIS International, Inc. (http://www.proiris.com) is a leader in automated urinalysis technology with systems in major medical institutions throughout the world. The Company's newest generation iQ®200 Automated Urine Microscopy Analyzer, utilizing image flow cytometry, patented flow microscope technology and neural network-based particle recognition, achieves a significant reduction in the cost and time-consuming steps involved in manual microscopic analysis. Iris Molecular Diagnostics is a development stage subsidiary with platform technologies for ultra-sensitive detection for high volume applications in microbiology, oncology and infectious diseases. The Company's Sample Processing business unit (formerly the StatSpin® subsidiary) (www.statspin.com), based in Westwood, Mass. manufactures innovative centrifuges and blood analysis products. Advanced Digital Imaging Research, LLC (ADIR) (www.adires.com), based near Houston, Texas, is the Company's imaging research and development subsidiary.

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